A vulnerability in a specific API of Cisco ISE and Cisco ISE-PIC could allow an unauthenticated, remote attacker to execute arbitrary code on the underlying operating system as root. The attacker does not require any valid credentials to exploit this vulnerability. This vulnerability is due to insufficient validation of user-supplied input. An attacker could exploit this vulnerability by submitting a crafted API request. A successful exploit could allow the attacker to obtain root privileges on an affected device.
CVE-2025-20281
Score elevated to 10.0 because this CVE is listed on the CISA Known Exploited Vulnerabilities catalog (added 2025-07-28), indicating real-world exploitation has been confirmed by US federal agencies. NVD baseline CVSS 10.0 retained for reference. Confidence: HIGH.
- Actively exploited in the wild (CISA-KEV)
No vendor fix yet — apply a workaround or compensating control (WAF / firewall / segmentation) and watch for a patch.
- CVSS v3
- 10.0
- EG Score
- 10.0(high)
- EG Risk
- 100(Act)EG Risk 100/100SSVC: Act
EG Risk is EchelonGraph's 0–100 priority score: it fuses intrinsic severity with real-world exploitation and automatability so you can rank equal-severity CVEs and fix the most dangerous first. Higher = act sooner. Distinct from the 0–10 EG Score (severity).
How it’s computedSeverity100% × 45%Exploitation100% × 40%Automatability100% × 15%Action: Fix now — active exploitation, automatable, high impact. - EPSS
- 99.9%
- KEV
- ⚠ Exploited
Published
June 25, 2025
Last Modified
October 28, 2025
Advisory Details (3)
Auto-updated Jul 18, 2026Zero Day Initiative — CVE-2025-20281: Cisco ISE API Unauthenticated Remote Code Execution Vulnerability
https://www.zerodayinitiative.com/blog/2025/7/24/cve-2025-20281-cisco-ise-api-unauthenticated-remote-code-execution-vulnerabilityKnown Exploited Vulnerabilities Catalog | CISA
Known Exploited Vulnerabilities Catalog | CISA. Listed in CISA Known Exploited Vulnerabilities catalog.
https://www.cisa.gov/known-exploited-vulnerabilities-catalog?field_cve=CVE-2025-20281Cisco Identity Services Engine Unauthenticated Remote Code Execution Vulnerabilities
https://sec.cloudapps.cisco.com/security/center/content/CiscoSecurityAdvisory/cisco-sa-ise-unauth-rce-ZAd2GnJ6Weakness Classification(1)
MITRE Common Weakness Enumeration — the root-cause categories this CVE belongs to.
Data Freshness Timeline
(refreshed 33× in last 7d / 178× in last 30d)
Each row is a source pipeline that fetched or updated this CVE on that date, with what changed. For example, "NVD update" means NVD published or revised its analysis for this CVE; "MITRE cvelistV5" means we ingested or refreshed it from the CNA feed. Most recent first.
Showing the most recent 100 of 360 total refreshes for this CVE.
- 2026-07-23 02:49 UTCEG score recompute
- 2026-07-22 20:59 UTCGHSA enrichment
- 2026-07-22 19:40 UTCCISA KEV update
- 2026-07-22 16:40 UTCEG score recompute
- 2026-07-22 16:40 UTCGHSA enrichment
- 2026-07-22 14:07 UTCEPSS rescore
- 2026-07-22 14:07 UTCEPSS rescore
- 2026-07-22 12:19 UTCGHSA enrichment
- 2026-07-22 07:59 UTCGHSA enrichment
- 2026-07-22 03:40 UTCGHSA enrichment
- 2026-07-21 23:20 UTCGHSA enrichment
- 2026-07-21 18:59 UTCGHSA enrichment
- 2026-07-21 14:40 UTCGHSA enrichment
- 2026-07-21 14:37 UTCCISA KEV update
- 2026-07-21 10:20 UTCGHSA enrichment
- 2026-07-21 06:01 UTCGHSA enrichment
- 2026-07-21 01:42 UTCGHSA enrichment
- 2026-07-20 21:23 UTCGHSA enrichment
- 2026-07-20 17:03 UTCGHSA enrichment
- 2026-07-20 12:42 UTCGHSA enrichment
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- 2026-07-20 04:04 UTCGHSA enrichment
- 2026-07-19 23:44 UTCGHSA enrichment
- 2026-07-19 19:25 UTCGHSA enrichment
- 2026-07-19 15:06 UTCGHSA enrichment
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- 2026-07-19 10:47 UTCGHSA enrichment
- 2026-07-19 06:28 UTCGHSA enrichment
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- 2026-07-18 21:49 UTCGHSA enrichment
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- 2026-07-17 06:56 UTCGHSA enrichment
- 2026-07-17 02:37 UTCGHSA enrichment
- 2026-07-16 22:18 UTCGHSA enrichment
- 2026-07-16 17:59 UTCGHSA enrichment
- 2026-07-16 17:04 UTCCISA KEV update
- 2026-07-16 17:02 UTCEPSS rescore
- 2026-07-16 17:02 UTCEPSS rescore
- 2026-07-16 13:40 UTCGHSA enrichment
- 2026-07-16 09:21 UTCGHSA enrichment
- 2026-07-16 05:01 UTCGHSA enrichment
- 2026-07-16 00:42 UTCGHSA enrichment
- 2026-07-15 20:23 UTCGHSA enrichment
- 2026-07-15 16:49 UTCCISA KEV update
- 2026-07-15 16:04 UTCGHSA enrichment
- 2026-07-15 15:04 UTCCISA KEV update
- 2026-07-15 11:45 UTCGHSA enrichment
- 2026-07-15 07:25 UTCGHSA enrichment
- 2026-07-15 03:06 UTCGHSA enrichment
- 2026-07-14 22:46 UTCGHSA enrichment
- 2026-07-14 18:27 UTCGHSA enrichment
- 2026-07-14 18:05 UTCCISA KEV update
- 2026-07-14 14:08 UTCGHSA enrichment
- 2026-07-14 09:48 UTCGHSA enrichment
- 2026-07-14 05:29 UTCGHSA enrichment
- 2026-07-14 01:10 UTCGHSA enrichment
- 2026-07-13 20:51 UTCGHSA enrichment
- 2026-07-13 17:07 UTCCISA KEV update
- 2026-07-13 16:32 UTCGHSA enrichment
- 2026-07-13 12:12 UTCGHSA enrichment
- 2026-07-13 07:52 UTCGHSA enrichment
- 2026-07-13 03:33 UTCGHSA enrichment
- 2026-07-12 23:14 UTCGHSA enrichment
- 2026-07-12 18:55 UTCGHSA enrichment
- 2026-07-12 14:36 UTCGHSA enrichment
- 2026-07-12 10:17 UTCGHSA enrichment
- 2026-07-12 05:58 UTCGHSA enrichment
- 2026-07-12 01:39 UTCGHSA enrichment
- 2026-07-11 21:20 UTCGHSA enrichment
- 2026-07-11 17:01 UTCGHSA enrichment
- 2026-07-11 12:42 UTCGHSA enrichment
- 2026-07-11 08:23 UTCGHSA enrichment
- 2026-07-11 04:03 UTCGHSA enrichment
- 2026-07-10 23:43 UTCGHSA enrichment
- 2026-07-10 19:25 UTCGHSA enrichment
- 2026-07-10 17:52 UTCCISA KEV update
- 2026-07-10 15:06 UTCGHSA enrichment
- 2026-07-10 10:46 UTCGHSA enrichment
- 2026-07-10 06:27 UTCGHSA enrichment
- 2026-07-10 02:07 UTCGHSA enrichment
- 2026-07-09 21:48 UTCGHSA enrichment
- 2026-07-09 17:29 UTCGHSA enrichment
- 2026-07-09 13:09 UTCGHSA enrichment
- 2026-07-09 08:50 UTCGHSA enrichment
- 2026-07-09 04:30 UTCGHSA enrichment
- 2026-07-09 00:12 UTCGHSA enrichment
- 2026-07-08 19:52 UTCGHSA enrichment
- 2026-07-08 15:33 UTCGHSA enrichment
- 2026-07-08 15:14 UTCEPSS rescore
- 2026-07-08 11:15 UTCGHSA enrichment
- 2026-07-08 06:56 UTCGHSA enrichment
- 2026-07-08 02:36 UTCGHSA enrichment
- 2026-07-07 22:17 UTCGHSA enrichment
- 2026-07-07 19:01 UTCCISA KEV update
Publicly available exploits
(4 references)Working exploit code is in the public domain (3 GitHub PoCs). Defenders should treat patch urgency accordingly — public PoCs typically lead to mass-exploitation within 24-72 hours.
- GitHub PoCill-deed/Cisco-CVE-2025-20281-illdeedFirst seen Jul 4, 2025
Unauthenticated Remote Code Execution exploit for CVE-2025-20281 in Cisco ISE ERS API. Execute commands or launch reverse shells as root — no authentication required.
Open source ↗ - GitHub PoCgrupooruss/CVE-2025-20281-CiscoFirst seen Jul 3, 2025
This script checks for the presence of the **CVE-2025-20281** vulnerability in Cisco Identity Services Engine (ISE) and ISE-PIC, which allows **unauthenticated remote code execution (RCE)** as root due to insufficient input validation in a specific API.
Open source ↗ - GitHub PoCabrewer251/CVE-2025-20281-2-Cisco-ISE-RCEFirst seen Jun 27, 2025
Unauthenticated Python PoC for CVE-2025-20281 RCE against ISE ERS API
Open source ↗ - Nucleihttp/cves/2025/CVE-2025-20281.yamlFirst seen Jan 1, 2025
Cisco ISE - Remote Code Execution
Open source ↗
Related CVEs(same CWE)
Same CWE
10 shownCWE-74
- CVE-2015-10062NVD 5.5EG 9.8MEDIUM
- CVE-2015-10027NVD 5.5EG 9.8MEDIUM
- CVE-2016-15007NVD 5.5EG 9.8MEDIUM
- CVE-2016-15004NVD 7.3EG 9.8HIGH
- CVE-2013-4144EG 9.8CRITICAL
- CVE-2013-7487EG 9.8CRITICAL
- CVE-2014-4678EG 9.8EPSS 92%CRITICAL
- CVE-2014-4967EG 9.8CRITICAL
- CVE-2014-4966EG 9.8CRITICAL
- CVE-2013-7381EG 9.8CRITICAL
Frequently asked(6)
What is CVE-2025-20281?
When was CVE-2025-20281 disclosed?
Is CVE-2025-20281 actively exploited?
What is the CVSS score of CVE-2025-20281?
Which products are affected by CVE-2025-20281?
How do I remediate CVE-2025-20281?
Dependency Blast Radius
Explore the affected products and dependency analysis for CVE-2025-20281
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