On BIG-IP versions 16.0.x before 16.0.1.1, 15.1.x before 15.1.2.1, 14.1.x before 14.1.4, 13.1.x before 13.1.3.6, and 12.1.x before 12.1.5.3, undisclosed requests to a virtual server may be incorrectly handled by the Traffic Management Microkernel (TMM) URI normalization, which may trigger a buffer overflow, resulting in a DoS attack. In certain situations, it may theoretically allow bypass of URL based access control or remote code execution (RCE). Note: Software versions which have reached End of Software Development (EoSD) are not evaluated.
CVE-2021-22991
Score elevated to 9.8 because this CVE is listed on the CISA Known Exploited Vulnerabilities catalog (added 2022-01-18), indicating real-world exploitation has been confirmed by US federal agencies. NVD baseline CVSS 9.8 retained for reference. Confidence: HIGH.
- Actively exploited in the wild (CISA-KEV)
No vendor fix yet — apply a workaround or compensating control (WAF / firewall / segmentation) and watch for a patch.
- CVSS v3
- 9.8
- EG Score
- 9.8(high)
- EG Risk
- 99(Act)EG Risk 99/100SSVC: Act
EG Risk is EchelonGraph's 0–100 priority score: it fuses intrinsic severity with real-world exploitation and automatability so you can rank equal-severity CVEs and fix the most dangerous first. Higher = act sooner. Distinct from the 0–10 EG Score (severity).
How it’s computedSeverity98% × 45%Exploitation100% × 40%Automatability100% × 15%Action: Fix now — active exploitation, automatable, high impact. - EPSS
- 99.1%
- KEV
- ⚠ Exploited
Published
March 31, 2021
Last Modified
October 27, 2025
Advisory Details (2)
Auto-updated Jun 1, 2026Known Exploited Vulnerabilities Catalog | CISA
Known Exploited Vulnerabilities Catalog | CISA. Listed in CISA Known Exploited Vulnerabilities catalog.
https://www.cisa.gov/known-exploited-vulnerabilities-catalog?field_cve=CVE-2021-22991Weakness Classification(3)
MITRE Common Weakness Enumeration — the root-cause categories this CVE belongs to.
Data Freshness Timeline
(refreshed 46× in last 7d / 206× in last 30d)
Each row is a source pipeline that fetched or updated this CVE on that date, with what changed. For example, "NVD update" means NVD published or revised its analysis for this CVE; "MITRE cvelistV5" means we ingested or refreshed it from the CNA feed. Most recent first.
Showing the most recent 100 of 388 total refreshes for this CVE.
- 2026-07-23 14:15 UTCEPSS rescore
- 2026-07-23 01:57 UTCEG score recompute
- 2026-07-22 22:07 UTCEG score recompute
- 2026-07-22 22:07 UTCGHSA enrichment
- 2026-07-22 19:40 UTCCISA KEV update
- 2026-07-22 17:43 UTCEG score recompute
- 2026-07-22 17:42 UTCGHSA enrichment
- 2026-07-22 14:05 UTCEPSS rescore
- 2026-07-22 13:19 UTCGHSA enrichment
- 2026-07-22 08:53 UTCGHSA enrichment
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- 2026-07-21 18:10 UTCEG score recompute
- 2026-07-21 18:10 UTCGHSA enrichment
- 2026-07-21 15:22 UTCEPSS rescore
- 2026-07-21 15:22 UTCEPSS rescore
- 2026-07-21 14:37 UTCCISA KEV update
- 2026-07-21 13:46 UTCGHSA enrichment
- 2026-07-21 09:23 UTCGHSA enrichment
- 2026-07-21 04:59 UTCGHSA enrichment
- 2026-07-21 00:35 UTCGHSA enrichment
- 2026-07-20 20:10 UTCEG score recompute
- 2026-07-20 20:10 UTCGHSA enrichment
- 2026-07-20 17:04 UTCEPSS rescore
- 2026-07-20 15:46 UTCGHSA enrichment
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- 2026-07-20 11:22 UTCGHSA enrichment
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- 2026-07-19 08:59 UTCGHSA enrichment
- 2026-07-19 04:34 UTCEG score recompute
- 2026-07-19 04:34 UTCGHSA enrichment
- 2026-07-19 02:26 UTCEPSS rescore
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- 2026-07-17 08:31 UTCEG score recompute
- 2026-07-17 08:30 UTCGHSA enrichment
- 2026-07-17 04:06 UTCGHSA enrichment
- 2026-07-16 23:43 UTCGHSA enrichment
- 2026-07-16 19:19 UTCGHSA enrichment
- 2026-07-16 17:04 UTCCISA KEV update
- 2026-07-16 17:00 UTCEPSS rescore
- 2026-07-16 14:54 UTCGHSA enrichment
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- 2026-07-15 21:19 UTCGHSA enrichment
- 2026-07-15 16:55 UTCEPSS rescore
- 2026-07-15 16:55 UTCEPSS rescore
- 2026-07-15 16:55 UTCGHSA enrichment
- 2026-07-15 16:49 UTCCISA KEV update
- 2026-07-15 15:04 UTCCISA KEV update
- 2026-07-15 12:31 UTCGHSA enrichment
- 2026-07-15 08:06 UTCGHSA enrichment
- 2026-07-15 03:41 UTCGHSA enrichment
- 2026-07-14 23:17 UTCGHSA enrichment
- 2026-07-14 18:51 UTCGHSA enrichment
- 2026-07-14 18:05 UTCCISA KEV update
- 2026-07-14 14:27 UTCGHSA enrichment
- 2026-07-14 10:03 UTCGHSA enrichment
- 2026-07-14 05:39 UTCGHSA enrichment
- 2026-07-14 01:15 UTCGHSA enrichment
- 2026-07-13 22:27 UTCEPSS rescore
- 2026-07-13 22:27 UTCEPSS rescore
- 2026-07-13 20:51 UTCGHSA enrichment
- 2026-07-13 17:07 UTCCISA KEV update
- 2026-07-13 16:27 UTCGHSA enrichment
- 2026-07-13 12:03 UTCGHSA enrichment
- 2026-07-13 07:39 UTCGHSA enrichment
- 2026-07-13 06:10 UTCEPSS rescore
- 2026-07-13 06:10 UTCEPSS rescore
- 2026-07-13 03:15 UTCGHSA enrichment
- 2026-07-12 22:52 UTCGHSA enrichment
- 2026-07-12 18:28 UTCGHSA enrichment
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- 2026-07-12 09:37 UTCGHSA enrichment
- 2026-07-12 05:44 UTCEPSS rescore
- 2026-07-12 05:44 UTCEPSS rescore
- 2026-07-12 05:13 UTCGHSA enrichment
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- 2026-07-11 20:26 UTCGHSA enrichment
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- 2026-07-11 08:25 UTCEPSS rescore
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- 2026-07-10 22:26 UTCGHSA enrichment
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- 2026-07-10 17:52 UTCCISA KEV update
- 2026-07-10 13:37 UTCGHSA enrichment
- 2026-07-10 09:10 UTCGHSA enrichment
Related CVEs(same CWE)
Same CWE
10 shownCWE-119 · CWE-120 · CWE-20
Frequently asked(6)
What is CVE-2021-22991?
When was CVE-2021-22991 disclosed?
Is CVE-2021-22991 actively exploited?
What is the CVSS score of CVE-2021-22991?
Which products are affected by CVE-2021-22991?
How do I remediate CVE-2021-22991?
Dependency Blast Radius
Explore the affected products and dependency analysis for CVE-2021-22991
Is Your Infrastructure Affected by CVE-2021-22991?
EchelonGraph automatically scans your cloud infrastructure and maps CVE exposure using blast radius analysis.